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. 2013 Oct 22;10(10):e1001534. doi: 10.1371/journal.pmed.1001534

Table 3. Year of HIV elimination (incidence <1/1,000 person-years) under universal testing and immediate ART for all HIV-infected patients (UTT) and number of life-years saved through UTT compared to the baseline of no UTT.

Model Sub-Model Year of Eliminationa (Range) Life-Years Saved per ART Treatment Year in 2050 (Range)
Model A 2019 (2018; 2021) 5.7 (4.7; 7.2)
+ Age structure (B1) 2019 (2018; 2020) 3.8 (3.1; 4.3)
+ Heterogeneity in HIV transmission by disease stageb (B2) 2053 (2048; >2060) 2.6 (2.1; 3.3)
Model B (B1 and B2 combined) 2053 (2042; >2060) 3.0 (2.6; 3.5)
+ Sexual network (C1) >2060 (2058; >2060) 2.6 (1.8; 2.9)
+ Background prevention interventions (C2) 2042 (2037; 2050) 2.8 (2.1; 3.2)
+ Up-to-date ART assumptions (C3) >2060 (2054; >2060) 2.9 (2.5; 3.1)
Model C (C1, C2, and C3 combined) 2032 (2030; 2041) 1.8 (1.1; 2.0)
Model D (STDSIM) 2029 (2027; 2034) 1.7 (1.2; 2.6)
Model D baseline (ART at CD4 count ≤350 cells/µl) 2041 (2037; 2047) N/A

UTT is scaled up linearly, starting in 2012 and reaching 90% coverage in 2019. Ranges reflect the variation in outcome due to the uncertainty in the parameter values that were quantified based on fitting the model to the data.

a

Incidence below 1/1,000 person-years.

b

We assumed four different stages: acute, asymptomatic, symptomatic, and AIDS.

N/A, not applicable.