Table 1.
Characteristics of included randomised controlled studies. Values are means (standard deviations) unless stated otherwise
| Variables | Morley (2008)7 | SUPPORT (2010)8 | Sandri (2010)10 | Dunn (2011)9 |
|---|---|---|---|---|
| Total No of participants | 610 | 1316 | 208 | 648* |
| Gestation (weeks) | 250/7-286/7 | 240/7-276/7 | 250/7-286/7 weeks | 260/7-296/7 |
| CPAP group: | ||||
| No in group | 307 | 663 | 103 | 223 |
| Birth weight (g) | 964 (212) | 834 (188) | 967 (221) | 1053 (252) |
| Gestational age (weeks) | 26.9 (1.0) | 26.2 (1.1) | 27.0 (1.0) | 28.1 (1.1) |
| Intubation group: | ||||
| No in group | 303 | 653 | 105 | 425 |
| Birth weight (g) | 952 (217) | 825 (198) | 913 (200) | 1040 (244) |
| Gestational age (weeks) | 26.9 (1.0) | 26.2 (1.1) | 27.0 (1.0) | 28.0 (1.1) |
| Timing of randomisation | After delivery | Before delivery | After delivery | After delivery |
| Stratification (weeks) | 250/7-266/7 and 270/7-286/7 | 240/7-256/7 and 260/7-276/7 | 250/7-266/7 and 270/7-286/7 | 260/7-276/7 and 280/7-296/7 |
CPAP=continuous positive airway pressure.
*Infants randomised to prophylactic surfactant group and intubate, surfactant, or extubate group were combined in the intubation group (prophylactic surfactant group, gestational age 28 (1.1 weeks) and birth weight 1040 g (244 g), intubate, surfactant, or extubate group gestational age 28.1 (1.1) and birth weight 1066 (270 g)).