Table 2.
Cancer spectrum of dutch family A members age 20 + and syndrome risk ≥25%
| Cancer sites | EPCAM family genetic test results | |||
|---|---|---|---|---|
| Pos + OGC* | Negative | Not tested | Total | |
| Colon | 10 | 0 | 5 | 15 |
| Skin | 0 | 0 | 0 | 0 |
| Esophagus | 0 | 0 | 1 | 1 |
| Duodenal | 1a | 0 | 0 | 1 |
| Stomach | 0 | 0 | 0 | 0 |
| Unknown primary | 0 | 0 | 0 | 0 |
| Breast | 2a | 0 | 0 | 2 |
| Upper urothelial tract | 1b | 0 | 0 | 1 |
| Lymphoma | 0 | 0 | 0 | 0 |
| Lung | 1 | 0 | 0 | 1 |
| Brain | 0 | 0 | 0 | 0 |
| Prostate | 0 | 0 | 0 | 0 |
| Pancreas | 1a | 0 | 0 | 1 |
| Testicle | 0 | 0 | 0 | 0 |
| Urinary bladder | 0 | 0 | 0 | 0 |
| Endometrium | 0 | 0 | 0 | 0 |
| Leukemia | 0 | 0 | 0 | 0 |
| Thyroid | 0 | 1c | 0 | 1 |
| Cervix | 0 | 1 | 0 | 1 |
| No cancer | 31 | 31 | 25 | 87 |
| Total individuals | 41 | 32 | 31 | 104 |
EPCAM, epithelial cell adhesion molecule; OGC, obligate gene carrier.
a
Individuals also diagnosed with colon cancer.
b
Also diagnosed with colorectal adenomas.
c
Also diagnosed with cervical cancer.