Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
| Compound | EC50 | FICcompound + FICACV | Inhibitory effect |
|---|---|---|---|
| HSV-2 | HSV-2 | ||
| Isolated HM alone | 1.5 ± 0.1 | - | - |
| Acyclovir alone | 2.9 ± 0.1 | - | - |
| Acyclovir + HM | 0.73 ± 0.1 | 0.92 | No interaction |
The interaction between HM and ACV was interpreted according to the combined FIC index [FICcompound + FICACV] as synergy (≤0.5), no interaction (0.5 - 4) or antagonism (>4) (32).
