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. 2013 Oct 22;8(10):e77937. doi: 10.1371/journal.pone.0077937

Table 3. Efficacy of HM ointment in HSV-2 genital infection model.

Drug Treatment No. of animals No. of animals survived No. of death Survival (%) Days-to-mortality (mean±S.D. days)a No. of vaginal samples containing HSV-2
Before treatment After treatment/death
HM 0.5% 20 14 06 70*b 11.15 ± 2.34* 20 07*
HM 0.25% 20 09 11 45* 9.45 ± 2.66* 20 15*
ACV 5% 20 16 04 80* 11.85 ± 1.33* 20 05*
Vaseline Base 20 02 18 10** 7.65 ± 2.87** 20 18**
Virus control 20 01 19 5 6.75 ± 1.93 20 19
Uninfected 20 20 0 100 NAc 0 0
a

Average time for mortality to occur following infection.

b P value from t-test between test group and virus control group. * P > 0.01; ** P < 0.05

c

Not applicable.