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. 2013 Oct 22;8(10):e78347. doi: 10.1371/journal.pone.0078347

Figure 2. Effects of fatigue loading on bone damage in Postn -/- and Postn +/+ mice.

Figure 2

(A-B) Basic fuschin staining of cracks in Postn +/+ and Postn -/- mice. (C) Cracks propagation visualized by 2D high resolution microCT (left panel), and confirmed by fuschin staining (right panel). (D) Cracks propagation from osteocyte lacunae to other osteocyte lacunae, visualized by 3D high resolution microCT (left panel), and confirmed by fuschin staining (right panel). * p<0.05,** p<0.01,*** p<0.001 indicate significant differences between fatigued tibia of Postn -/- vs Postn +/+. Bars show mean (± sem), intermittent line: Postn -/-, continuous line: Postn +/+.