Table 1. GRAPES vs GraphGrepSX and SING.

	GRAPES	GraphGrepSX	SING	Description
TRIE indexing	x	x		Compact indexing. Efficiency on indexing and filtering
	x	x
Path indexing	x	x	x	Lighter than subgraphs or trees
Store path node	x		x	More filtering power
Parallel Indexingand Matching	x			Necessary for biological data size and density
Connected components	x			Load balancing onto CPU cores

List of the new GRAPES components together with the components of GRAPES taken from GraphGrepSX [16] and SING [15].