Table 2. List of compounds selected from virtual screening and tested against OASS-B.
Compound | Specs code | Kd (µM) |
13 | AK-564/25068019 | 33±2 |
14 | AI-204/34859016 | 810±110 |
15 | AP-402/41884919 | >1500 |
16 | AG-664/25098006 | >1500 |
17 | AH-262/34614012 | >1500 |
18 | AC-776/15493018 | >1500 |
19 | AE-848/08323031 | >1500 |
20* | AG-690/12134163 | n.d. |
21 | AG-205/34690008 | >1500 |
22 | AO-080/42837941 | > 1500 |
23 | AK-968/41172226 | >1500 |
due to the strong emission at 500 nm for excitation at 412 nm, this compound was assayed at concentrations lower than 100 µM and no binding was observed.