Figure 2. Effect of DSS and/or H. polygyrus infection on IL-12p70, IL-6, IL-22, IL-17A, IL-10, TGF-β (pg/mL, A) and MCP-1 concentration (ng/ml, B) in the small intestine at 6 and 15 days post infection with H. polygyrus and mean absorbance (OD) of intestinal mucus IgG1, IgA and IgE against somatic H. polygyrus L4 and adults (C).

The concentration of cytokines in the small intestine of mice treated for colitis with dextran sulphate sodium (COL); infected with H. polygyrus (HP) or treated for colitis and infected with H. polygyrus (HP/COL) and the specific antibodies levels were measured by ELISA. The results are expressed as the means ± SE of five mice. Statistical significance between groups was assessed by ANOVA; *P < 0.05 compared to values obtained in the small intestine of control untreated mice infected with H. polygyrus (HP).