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. 2013 Oct 22;8(10):e78034. doi: 10.1371/journal.pone.0078034

Figure 4. The consequences of colitis in H. polygyrus nematodes.

Figure 4

A. The mean number of L4 and adult worms isolated from mice with colitis infected with H. polygyrus (HP/COL) and from control infection (HP). B. The mean worm position (fraction of intestine length). C. Mean worm length of male and female L4, and adult H. polygyrus (mm). D. Sex ratio (male: female; P<0.001 Chi-square test); BALB/c mice were orally infected with 300 H. polygyrus L3, 3 days after DSS treatment. The mice were sacrificed at day 6 and 15 post infection. Tissue –dwelling larvae and adults were counted in situ to determine the total number and distribution along small intestine. Individuals were removed, sexed and measured. The mean larval position was calculated as (number of larvae per segment x distance of segment from stomach) divided by (total larvae x intestine length). Each data point represents the means ± SE of five mice. *P < 0.05 comparing to the level of control mice infected with H. polygyrus.