(b) Required number of centers N for varying number of within center subjects n and baseline rate β0, while β1 = 0.18 and σ2 = 0.5 were fixed. | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|
−1.6 (0.20) | −1.2 (0.30) | −0.8 (0.45) | −0.4 (0.67) | 0 (1.0) | 0.4 (1.49) | 0.8 (2.23) | 1.2 (3.32) | 1.6 (4.95) | ||
20 |
Np
NOA |
179 (0.82) 258 |
120 (0.82) 181 |
81 (0.82) 130 |
54 (0.84) 95 |
36 (0.83) 72 |
25 (0.80) 56 |
17 (0.82) 46 |
11 (0.80) 39 |
8 (0.83) 34 |
50 |
Np
NOA |
72 (0.82) 104 |
48 (0.81) 73 |
33 (0.82) 52 |
22 (0.83) 38 |
15 (0.81) 29 |
10 (0.81) 23 |
7 (0.79) 19 |
5 (0.85) 16 |
3 (0.76) 14 |
200 |
Np
NOA |
18 (0.82) 26 |
12 (0.82) 19 |
9 (0.85) 13 |
6 (0.82) 10 |
4 (0.81) 8 |
3 (0.84) 6 |