Skip to main content
. Author manuscript; available in PMC: 2014 Nov 1.
Published in final edited form as: Gastroenterology. 2013 Jul 25;145(5):1088–1097.e8. doi: 10.1053/j.gastro.2013.07.027

Figure 1. Acinar cells lacking Numb are incapable of regeneration and have reduced metaplastic capacity.

Figure 1

(A) Gross morphology, (B) H&E staining, (C) immunostaining for E-cadherin (green), counterstained with DAPI (blue), and (D) immunostaining for Amylase (green) and CK19 (red), counterstained with DAPI (blue) of p48Cre versus p48Cre;Numbf/f 7 days after caerulein treatment. , Scale bars represent 100µm. (E) Pancreas mass:body weight ratio of PBS and caerulein treated mice at day 7. * P<0.05, N=3–5.