Table 2.
Risk Ratio predicting smoking versus abstinence during various time points for a one standard deviation increase in each smoking topography measure.
| Abstinence Outcomes | Puff Volume (ml) | Total Puff Volume (ml) | Average Flow (ml/sec) | Peak Flow (ml/sec) | Duration (msec) | |||||
|---|---|---|---|---|---|---|---|---|---|---|
|
| ||||||||||
| RR (95% CI) | P | RR (95% CI) | P | RR (95% CI) | P | RR (95% CI) | P | RR (95% CI) | P | |
| First Cigarette Smoked | ||||||||||
| Last 7 Days | 0.87 (0.69–1.11) | 0.263 | 0.93 (0.70–1.23) | 0.591 | 0.87 (0.69–1.09) | 0.230 | 0.89 (0.71–1.12) | 0.325 | 0.97 (0.76–1.25) | 0.830 |
| Last 2 Weeks | 1.01 (0.76–1.34) | 0.962 | 1.03 (0.74–1.45) | 0.844 | 0.89 (0.68–1.17) | 0.416 | 1.01 (0.78–1.31) | 0.944 | 1.14 (0.84–1.56) | 0.397 |
| Last 4 Weeks | 1.01 (0.69–1.47) | 0.962 | 1.22 (0.75–1.97) | 0.418 | 0.84 (0.58–1.22) | 0.353 | 0.97 (0.68–1.38) | 0.859 | 1.44 (0.95–2.19) | 0.089 |
| Follow Up - 7 Day PPA | 1.00 (0.65–1.56) | 0.984 | 0.99 (0.62–1.58) | 0.966 | 0.87 (0.58–1.30) | 0.499 | 0.95 (0.66–1.38) | 0.786 | 1.42 (0.92–2.19) | 0.116 |
|
| ||||||||||
| All Cigarettes Smoked | ||||||||||
| Last 7 Days | 0.90 (0.71–1.14) | 0.380 | 1.03 (0.78–1.37) | 0.809 | 0.90 (0.72–1.14) | 0.388 | 0.93 (0.74–1.17) | 0.552 | 0.96 (0.75–1.23) | 0.731 |
| Last 2 Weeks | 1.05 (0.78–1.42) | 0.759 | 1.10 (0.78–1.55) | 0.590 | 0.92 (0.70–1.21) | 0.570 | 1.05 (0.80–1.38) | 0.705 | 1.13 (0.83–1.54) | 0.446 |
| Last 4 Weeks | 1.09 (0.72–1.65) | 0.699 | 1.46 (0.87–2.45) | 0.156 | 0.86 (0.57–1.30) | 0.479 | 1.01 (0.69–1.49) | 0.950 | 1.39 (0.85–2.28) | 0.194 |
| Follow Up - 7 Day PPA | 0.99 (0.67–1.46) | 0.964 | 1.01 (0.65–1.57) | 0.970 | 0.73 (0.51–1.05) | 0.089 | 0.87 (0.62–1.21) | 0.406 | 1.51 (0.98–2.35) | 0.064 |
Data are shown as the risk ratio and 95% confidence interval of smoking versus abstinence for a one standard deviation unit increase in the topography measures adjusted for treatment assignment from parent study (VAR vs. TNP). Abstinence was determined based on an intent-to-treat sample and missing data were assumed as smoking at various time points. Units of change (one Standard Deviation) in smoking topography measures used for RR calculations (first cigarette smoked, all cigarettes smoked): Per Puff Volume (16.9, 15.9 mL), Total Puff Volume (255, 793 mL), Average Flow per Puff (9.0, 8.2 mL/Sec), Peak Flow per Puff (14.7, 13.8 mL/Sec), and Puff Duration (464,457 msec). PPA refers to 7-day point prevalence abstinence at the 8-week follow-up visit.