Table 3.
Association of prenatal urinary BPA concentration (log2, specific gravity adjusted) and continuous behavior outcomes at 7 years of age. CHAMACOS Study, Salinas, California.
| Boys | Girls | BPA × Sex | |||
|---|---|---|---|---|---|
| N | β(9’5% CI) | N | β(95%CI) | p-value | |
| Mother reporta | |||||
| BASC-2 | |||||
| Internalizing Problems | 133 | 1.8 (0.3,3.3) * | 155 | 0.0 (−1.4,1.3) | 0.04 |
| Anxiety scale | 133 | 1.5 (−0.3,3.2) † | 155 | 0.5 (−0.8,1.8) | 0.30 |
| Depression scale | 135 | 1.5 (0.0,3.0 )* | 156 | 0.1 (−1.2,1.3) | 0.10 |
| Somatization scale | 133 | 1.3 (−0.1,2.7) † | 155 | −0.7 (−2.2,0.8) | 0.03 |
| Externalizing Problems | 133 | 0.7 (−1.1,2.5) | 155 | −0.3 (−1.3,0.7) | 0.14 |
| Aggression scale | 135 | 0.5 (−1.2,2.1) | 156 | 0.2 (−0.8,1.1) | 0.35 |
| Conduct problems scale | 133 | 1.1 (−0.7,3) | 155 | −0.9 (−2.1,0.4) | 0.02 |
| Hyperactivity scale | 133 | 0.1 (−1.5,1.8) | 155 | −0.3 (−1.2,0.7) | 0.62 |
| Attention scale | 133 | −0.2 (−1.1,0.8) | 155 | −0.3 (−1.1,0.4) | 0.66 |
| CADS | |||||
| Inattention DSM-IV | 135 | 0.1 (−1.3,1.5) | 156 | −0.5 (−1.5,0.5) | 0.59 |
| Hyperactive DSM-IV | 135 | 0.3 (−1.3,1.9) | 156 | 0.0 (−1.1,1.1) | 0.83 |
| ADHD DSM-IV | 135 | 0.3 (−1.2,1.8) | 156 | −0.2 (−1.3,0.8) | 0.69 |
| Teacher reportb | |||||
| BASC-2 | |||||
| Internalizing Problems | 114 | 2.5 (0.7,4.4) ** | 131 | −1.0 (−3.1,1.1) | 0.03 |
| Anxiety scale | 114 | 1.9 (0.0,3.7) * | 131 | −1.7 (−3.7,0.4) | 0.01 |
| Depression scale | 114 | 3.2 (1.4,5.1) ** | 131 | −0.2 (−1.8,1.4) | 0.01 |
| Somatization scale | 114 | 0.8 (−1.1,2.8) | 131 | −0.5 (−2.9,1.8) | 0.51 |
| Externalizing Problems | 114 | 1.8 (−0.5,4.1) | 131 | −0.5 (−1.8,0.8) | 0.07 |
| Aggression scale | 114 | 2.7 (0.3,5.1)* | 131 | −0.1 (−1.4,1.1) | 0.04 |
| Conduct problems scale | 114 | 1.1 (−0.9,3.1) | 131 | −0.3 (−1.7,1.1) | 0.26 |
| Hyperactivity scale | 114 | 1.1 (−1.3,3.4) | 131 | −0.9 (−2.2,0.4) | 0.11 |
| Attention scale | 114 | −0.1 (−1.4,1.2) | 131 | −0.4 (−1.3,0.5) | 0.62 |
| CADS | |||||
| Inattention DSM-IV | 114 | 0.3 (−1.5,2.2) | 130 | −0.6 (−1.9,0.7) | 0.38 |
| Hyperactive DSM-IV | 114 | 1.4 (−0.6,3.5) | 130 | −1.6 (−3.3,0.2) † | 0.03 |
| ADHD DSM-IV | 113 | 0.8 (−1.2,2.7) | 127 | −1.2 (−2.9,0.4) | 0.13 |
a
Adjusted for mother's country of birth, maternal education, marital status, maternal language of interview, child's exact age, HOME score, household income, number of siblings, maternal depression at 7 years, child's BPA at 5 years, and maternal DAP metabolite levels during pregnancy.
b
Adjusted for mother's country of birth, maternal education, marital status, child's age, HOME score, household income, number of siblings, child's BPA at 5 years and maternal DAP metabolite levels during pregnancy.
†
p<0.1;
*
p<0.05;
**
p<0.01