Table 2.
Comparison of Clinicopathologic and Perioperative Characteristics between Patients with Lipomas and Patients with Atypical Lipomatous Tumors
| Clinicopathologic variable n (%), or mean* |
Lipomas (n=256) |
ALTs (n=63) |
p Value |
|---|---|---|---|
| Clinical characteristics | |||
| Age, y* | 53.5 | 60.5 | <0.0001 |
| Age ≥55 y | 116 (45.3) | 45 (71.4) | <0.0001 |
| Male sex | 120 (46.9) | 28 (44.4) | 0.837 |
| Race | |||
| White | 124 (49.4) | 39 (61.9) | 0.205 |
| Black | 76 (30.3) | 14 (22.2) | |
| Other | 51 (20.3) | 10 (15.9) | |
| Location | |||
| Torso | 101 (39.5) | 7 (11.1) | <0.0001 |
| Upper Extremity | 81 (31.6) | 5 (7.9) | |
| Lower Extremity | 74 (28.9) | 51 (81) | |
| Extremity location (vs torso) | 155 (60.5) | 56 (88.9) | <0.0001 |
| Estimated duration of mass, mo* | 31.6 | 30.4 | 0.877 |
| Prior operation at same site† | 15 (5.9) | 13 (20.6) | 0.001 |
| Excision immediately prior to presentation | 2 (0.8) | 8 (12.7) | <0.0001 |
| 3-dimensional imaging (MRI or CT) | 211 (86.5) | 58 (98.3) | 0.006 |
| Preoperative tissue diagnosis | 27 (10.8) | 17 (27.9) | 0.001 |
| Neoadjuvant radiation therapy | 0 | 2 (3.3) | 0.037 |
| Perioperative characteristics | |||
| Operation | |||
| Local excision | 115 (44.9) | 4 (6.3) | <0.0001 |
| Radical excision | 141 (55.1) | 59 (93.7) | |
| Complication, any | 22 (9.8) | 8 (13.6) | 0.554 |
| Wound complication requiring reoperation | 4 (1.8) | 3 (5.1) | 0.162 |
| Postoperative radiation therapy | 0 | 2 (3.4) | 0.040 |
| Pathologic characteristics | |||
| Tumor size, cm | 8.3 | 16.0 | <0.0001 |
| Tumor size ≥10 cm | 83 (32.5) | 51 (83.6) | <0.0001 |
| Margin | |||
| Negative | 8 (3.1) | 28 (44.4) | <0.0001 |
| Positive | 2 (0.8) | 15 (23.8) | |
| Not reported | 246 (96.1) | 20 (31.7) | |
| Outcomes | |||
| Recurrence | 2 (0.8) | 14 (22.6) | <0.0001 |
| Follow-up, mo | 27.6 | 44.2 | 0.168 |
*
Continuous variables were compared using student’s t test; the mean is reported.
†
Exclusive of excision immediately prior to referral.