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. Author manuscript; available in PMC: 2014 Sep 1.
Published in final edited form as: Pharmacol Biochem Behav. 2013 Jul 1;110:112–116. doi: 10.1016/j.pbb.2013.06.010

Figure 1.

Figure 1

Conditioned place preference as reflected by the increased number of seconds spent in the oxycodone- (for oxycodone conditioned group) or saline- (for saline conditioned group) paired compartment in the postconditioning sessions (postconditioning time minus preconditioning time) in groups given oxycodone or saline (mean ±S.E.M., n=7 per group). Oxycodone produced a dose dependent preference for oxycodone-paired compartment in both age groups (*p<0.05 and *p<0.01 vs. saline in the adult group: #p<0.05 and ###p<0.001 vs. saline in the adolescent group). However, the adult mice developed conditioned preference to the lowest dose of oxycodone tested (0.3 mg/kg); the adolescent group did not ($p>0.05 between age groups).