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Arousals resulting from events of sleep apnea were characterized by heart rate elevations (upper left panel). Heart rate elevations were not associated with PLMs (lower left panel). However, during baseline recordings, leg movements were characterized by the usual peak at 20-30 seconds in the distribution of inter-movement intervals (right panels). The peak was suppressed by pramipexole. PLMS, periodic leg movements during sleep; PLMW, periodic leg movements during wakefulness.
