Table 2. Association between Fracture type and Quartiles of FGF23.
HR (95%CI) | OR(95% CI) | |||
---|---|---|---|---|
|
||||
FGF23 Quartiles | Nonspine fractures (N=386) | Hip Fractures (N=73) | † Major Osteoporotic fractures (N=109) | † Incident Vertebral Fractures (N=52) |
N=386 | N=73 | N=109 | N=52 | |
Q1 (ref) | 1.0 | 1.0 | 1.0 | 1.0 |
Q2 | 1.2 0.09-1.6) | 1.6 (0.8-3.4) | 0.6 (0.4-1.1) | 0.47 (0.2-1.08) |
Q3 | 1.1 (0.8-1.5) | 1.6 (0.7-3.4) | 0.8 (0.5-1.3) | 0.49 (0.21-1.14) |
Q4 | 1.2 (0.9-1.7) | 1.6 (0.7-3.5) | 0.7 (0.4-1.2) | 0.81 (0.39-1.66) |
P trend | 0.43 | 0.3 | 0.3 | 0.61 |
Q4 vs rest | 1.1 (0.85-1.43) | 1.15 (0.66-2.02) | 0.91 (0.76-1.09) | 1.25 (0.67-2.33) |
Quartile cut-points 12.2, 16.6, 22.4 pg/ml
Models adjusted for age, race, clinic site and BMI
= fractures occurring in the random cohort only