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. Author manuscript; available in PMC: 2014 Nov 1.
Published in final edited form as: J Bone Miner Res. 2013 Nov;28(11):2325–2332. doi: 10.1002/jbmr.1985

Table 2. Association between Fracture type and Quartiles of FGF23.

HR (95%CI) OR(95% CI)

FGF23 Quartiles Nonspine fractures (N=386) Hip Fractures (N=73) Major Osteoporotic fractures (N=109) Incident Vertebral Fractures (N=52)
N=386 N=73 N=109 N=52
Q1 (ref) 1.0 1.0 1.0 1.0
Q2  1.2 0.09-1.6) 1.6 (0.8-3.4) 0.6 (0.4-1.1)  0.47 (0.2-1.08)
Q3  1.1 (0.8-1.5) 1.6 (0.7-3.4) 0.8 (0.5-1.3)  0.49 (0.21-1.14)
Q4  1.2 (0.9-1.7) 1.6 (0.7-3.5) 0.7 (0.4-1.2)  0.81 (0.39-1.66)
P trend 0.43  0.3 0.3 0.61
Q4 vs rest 1.1 (0.85-1.43) 1.15 (0.66-2.02)  0.91 (0.76-1.09)  1.25 (0.67-2.33)

Quartile cut-points 12.2, 16.6, 22.4 pg/ml

Models adjusted for age, race, clinic site and BMI

= fractures occurring in the random cohort only