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. Author manuscript; available in PMC: 2014 Nov 30.
Published in final edited form as: Psychiatry Res. 2013 Jun 15;210(1):287–293. doi: 10.1016/j.psychres.2013.05.026

Figure 1.

Figure 1

QQ plot and visualization of differentially expressed genes.

Left panel (a): It shows a quantile-quantile (QQ) plot in which the expected distribution of −log10(p-value) is compared to the observed distribution. The gray area denotes 95% confidence bands for the expected distribution. The observed distribution deviates sharply from the expected, consistent with a small number of genes with differential expression. Right panel (b): The top 100 differentially expressed genes identified using gene-wise dispersion are highlighted in red. The orange points on the left represent transcripts with counts of zero at either T1 or T2. Blue lines denote log2FC of ±2. (FC is fold change.)