Table 1.
Top two functional clusters from gene-set enrichment analysis of top 100 genes using DAVID.
| Annotation Cluster 1 | Enrichment Score: 4.62 | ||||||
|---|---|---|---|---|---|---|---|
| Category | Term | Count€ | PValue | Pop Hits |
Fold Enrichment |
FDR | Up vs. Down£ |
| SP_PIR_KEYWORDS | disulfide bond | 26 | 5.86E-08 | 2924 | 3.10975 | 7.01E-05 | 17/2 |
| UP_SEQ_FEATURE | disulfide bond | 25 | 1.57E-07 | 2819 | 3.081847 | 2.00E-04 | 17/8 |
| SP_PIR_KEYWORDS | signal | 22 | 9.75E-05 | 3250 | 2.367385 | 0.116642 | 14/8 |
| UP_SEQ_FEATURE | signal peptide | 22 | 1.07E-04 | 3250 | 2.352369 | 0.136868 | 14/8 |
| GOTERM_CC_FAT | GO:0005576~extracellular region |
16 | 9.13E-04 | 2010 | 2.422554 | 1.016557 | 13/3 |
| SP_PIR_KEYWORDS | Secreted | 13 | 0.002134 | 1689 | 2.691803 | 2.524341 | 10/3 |
| Annotation Cluster 2 | Enrichment Score: 2.58 | ||||||
| Category | Term | Count | PValue | Pop Hits |
Fold Enrichment |
FDR | Up vs. Down |
| GOTERM_BP_FAT | GO:0006952~defense response |
9 | 8.46E-04 | 615 | 4.303712 | 1.271136 | 7/2 |
| SP_PIR_KEYWORDS | antibiotic | 4 | 9.21E-04 | 68 | 20.57219 | 1.097168 | 4/0 |
| SP_PIR_KEYWORDS | Antimicrobial | 4 | 0.001044 | 71 | 19.70294 | 1.243026 | 4/0 |
| GOTERM_BP_FAT | GO:0042742~defense response to bacterium |
4 | 0.006089 | 112 | 10.50311 | 8.819647 | 4/0 |
| GOTERM_BP_FAT | GO:0009617~response to bacterium |
4 | 0.026167 | 193 | 6.095066 | 33.02563 | 4/0 |
€
number of genes in each functional category
£
Number of up-regulated genes versus down-regulated genes