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Atp6v1c1 knockdown inhibits primary 4T1 mouse mammary tumor metastasis and prolongs survival after xenograft in vivo. A. Representative H&E staining of lungs and livers (scale bar: 100μm) as indicated. Black arrows indicate the metastases. B. Number of mice bearing metastases in the lungs, liver, and bone from a primary mammary tumor based on H&E staining at day 33 (n=12 mice). Numbers indicate the number of mice bearing metastases. C. Survival of mice bearing tumors (n=15) over time.
