Table 1.
Candida adhesin | Host cell receptor | References |
---|---|---|
Integrin analog (INT) | iC3b, Arginine–glycine–aspartic acid (RGD) | (8– 11) |
Fibronectin adhesin (FN) | Fibronectin and vitronectin receptors | (12–14) |
Fucoside-binding adhesin | Glycoside (glycoprotein or glycolipid) receptor | (15–18) |
GlcNAc-binding protein | N-Acetylglucosamine | (15–17) |
Fimbrial adhesin | βGalNAc(1–4β-Gal) | (19) |
Hyphal wall protein 1 (HWP1) | A substrate of epithelial cell-associated transglutaminases facilitating cross-linking with epithelial cells | (20, 21) |
Agglutinin-like sequence (ALS) family | Multiple receptors including E-cadherin, N-cadherin and host cell ferritin | (22–25) |
Enhanced adherence to polystyrene (EAP1) | Host cell targets not yet identified | (26–27) |