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G-protein signaling pathways activated by mGluR1a. This drawing represents an overview of G-protein dependent signaling pathways that are activated upon Glu binding to mGluR1a. Following receptor activation and downstream of G-protein dissociation, the following second messenger systems are activated in the nervous system: PKB, PLCγ, PI3K/AKT/mTorC1 and 2, IP3/DAG, NFκB and CaM. Please see the text for detailed description on these signaling pathways.
