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Immunohistochemical study of an endometrial endometrioid carcinoma with coexisting high-grade (A) and low-grade (B, C) components. The high-grade component is negative for ARID1A (D) while the low-grade component has areas with retained ARID1A staining (E) and areas with clonal loss of ARID1A (F) (A-F, ×200).
