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. 2013 Sep 21;10(12):1639–1648. doi: 10.7150/ijms.6960

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© Ivyspring International Publisher. This is an open-access article distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited.

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S. typhimurium-mediated Apoptin induced apoptosis and reduced viability of Hep-2 cells. (A).ST-rC-Apoptin induced apoptosis in Hep-2 cells measured by the increase of Annexin V- PI positive cells. (A: apoptotic cells; V: viable cells). (B). Flow cytometry analysis showed viable, early and late apoptotic cells. Data was presented as mean ± S.E, n=2, *p<0.05. (C). MTT assays indicated that tumour cell viability was significantly reduced with ST-rC-Apoptin treatment. Data was presented as mean ± S.E, n=3, *p<0.05.