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. 2013 Sep 21;10(12):1639–1648. doi: 10.7150/ijms.6960

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© Ivyspring International Publisher. This is an open-access article distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited.

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S. typhimurium-mediated Apoptin increased the activity of caspase-3 and involved in Bax, cleaved caspase-9 and Cytochrome c expression. (A). Caspase 3/8 activity was measured at 48 hours post-infection with either ST-rC-Apoptin or ST-rC-EGFP compared with mock-infected cells. Data was presented as mean ± SE; at least two independent experiments conducted in triplicate; *p < 0.05. (B). Western blotting for Cytochrome c, Bcl-2, caspase-9 (cleaved caspase-9) and Bax protein expression in Hep-2 cells at 48 hours post-infection. n=3.