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Tumour specific distribution of S. typhimurium-mediated Apoptin. (A). Systemic inoculation of 1×107 cfu ST-rC-Apoptin resulted in the preferential colonization of bacteria within the tumour at a 1,000-fold increase compared to liver tissue in both single and redosing treatment. Data was presented as mean ± SE, n=5 mice/group. (B). Histological staining in the major organs of the mice. a. Brain; b. Heart; c. Lung; d. Liver; e. Kidney; f. Spleen.
