Table 1.
Correlation between proteins expression and clinicopathological parameters of GC patients (Chi-square test).
| Variable | DJ-1 expression | PTEN expression | Abnormal expression of DJ-1 and PTEN | |||
|---|---|---|---|---|---|---|
| Low (n=38) | High (n=76) | Low (n=67) | High (n=47) | No (n=63) | Yes (n=51) | |
| Age (year) | ||||||
| <55 (n=53) | 17 | 36 | 32 | 21 | 26 | 27 |
| ≥55 (n=61) | 21 | 40 | 35 | 26 | 37 | 24 |
| P=0.806 | P=0.782 | P=0.206 | ||||
| Gender | ||||||
| Male (n=72) | 24 | 48 | 41 | 31 | 43 | 29 |
| Female (n=42) | 14 | 28 | 26 | 16 | 20 | 22 |
| P=1.000 | P=0.647 | P=0.211 | ||||
| Tumor differentiation | ||||||
| Well and moderate (n=67) | 21 | 46 | 37 | 30 | 36 | 31 |
| Poor (n=47) | 17 | 30 | 30 | 17 | 27 | 20 |
| P=0.541 | P=0.409 | P=0.750 | ||||
| Tumor depth | ||||||
| T1-2 (n=26) | 14 | 12 | 12 | 14 | 20 | 6 |
| T3-4 (n=88) | 24 | 64 | 55 | 33 | 43 | 45 |
| P=0.003 | P=0.103 | P=0.001 | ||||
| Lymph node metastasis | ||||||
| N0 (n=40) | 19 | 21 | 20 | 20 | 28 | 12 |
| N1-3 (n=74) | 19 | 55 | 47 | 27 | 35 | 39 |
| P=0.011 | P=0.190 | P=0.012 | ||||
| Distant metastasis | ||||||
| M0 (n=92) | 36 | 56 | 47 | 45 | 61 | 31 |
| M1 (n=22) | 2 | 20 | 20 | 2 | 2 | 20 |
| P=0.001 | P=0.001 | P=0.001 | ||||
| Clinical stage | ||||||
| Early stage (n=40) | 21 | 19 | 17 | 23 | 32 | 8 |
| Advanced stage (n=74) | 17 | 57 | 50 | 24 | 31 | 43 |
| P=0.001 | P=0.018 | P=0.001 | ||||
| PTEN expression | ||||||
| Low expression (n=67) | 16 | 51 | ||||
| High expression (n=47) | 22 | 25 | ||||
| P=0.006 | ||||||