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. 2013 Sep 27;10(12):1702–1714. doi: 10.7150/ijms.7114

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© Ivyspring International Publisher. This is an open-access article distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited.

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Fig 3 — Expression of VEGF in lung tissue. (A) Western blot analysis showed that the level of VEGF protein was significantly decreased in comparison to the group administered a nonsilencing oligoneucleotide (CON) at days 2, 4, and 7 after VEGF siRNAs administration. Lewis lung carcinoma cell line (LLC) is also shown for comparison. Administration of recombinant VEGF 2 days after VEGF siRNA administration significantly increased the VEGF protein level at day 4, almost to the level of the CON group. (B) Administration of DCI 2 days after VEGF siRNAs administration significantly increased the VEGF protein level at day 4, almost to the level of the CON group. Lines separate different lanes from one gel. (C) Administration of TTF-1 siRNAs reduced VEGF protein level 2 days after. n=4 in each group. *p<0.05 vs CON group.

Fig 3 — Expression of VEGF in lung tissue. (A) Western blot analysis showed that the level of VEGF protein was significantly decreased in comparison to the group administered a nonsilencing oligoneucleotide (CON) at days 2, 4, and 7 after VEGF siRNAs administration. Lewis lung carcinoma cell line (LLC) is also shown for comparison. Administration of recombinant VEGF 2 days after VEGF siRNA administration significantly increased the VEGF protein level at day 4, almost to the level of the CON group. (B) Administration of DCI 2 days after VEGF siRNAs administration significantly increased the VEGF protein level at day 4, almost to the level of the CON group. Lines separate different lanes from one gel. (C) Administration of TTF-1 siRNAs reduced VEGF protein level 2 days after. n=4 in each group. *p<0.05 vs CON group.