Skip to main content
. Author manuscript; available in PMC: 2013 Oct 23.
Published in final edited form as: J Immunol. 2010 Jul 23;185(5):3019–3027. doi: 10.4049/jimmunol.1000879

FIGURE 4.

FIGURE 4

Increased frequency of immature transitional and mature activated B cell subsets in peripheral blood of chronic HCV-infected subjects. Intravenous whole blood samples were stained with B cell phenotyping markers (CD10, CD19, CD20, CD21, CD27, and CD38) and analyzed for B cell subsets by flow cytometric analysis. Proportion of forward and side scattered lymphocytes that express CD19 are shown in A. B cell subset analysis was performed as shown in B. Proportions of CD19-gated cells that were CD10+CD27− (C, immature/transitional B cells), CD10−CD21+CD27− (D, naive B cells), CD10−CD21+CD27+ (E, resting memory B cells), CD10−CD21−CD27+ (F, mature/activated B cells), CD10−CD21−CD27− (G, tissue-like memory B cells), and CD20−CD38+ (H, plasma cells) were determined for HCV-infected (n = 24) and healthy control (n = 25) subjects.