Table 1.

SINE IC₅₀ values of normal, leukemic, and multiple myeloma log-phase cell lines with 48-hour drug exposure by CT-Blue assay.

	KPT127 (µM)			KPT185 (µM)			KPT249 (µM)			KPT276 (µM)			KPT330 (µM)
	Mean	SEM	n	Mean	SEM	n	Mean	SEM	n	Mean	SEM	n	Mean	SEM	n
PBMCs	13.6	0.99	5	13.1	1.0	6	18.3	1.7	6	74.6	15.6	4	16.9	1.76	4
Flow20001	27.0	2.5	2	12.6	5.0	6	19.2	5.2	3	26.14		1	26.4		1
Wi-381	16.8	4.3	2	11.1	4.0	5	13.4	5.1	3	3.52	0.55	3	10.5		1
HL-602	1.54	0.19	2	0.17	0.04	7	0.25	0.10	3	0.57	0.20	3	3.5	3.4	3
H9293	0.86	0.05	2	0.12	0.02	9	0.17	0.03	5	0.32	0.04	5	0.115	0.005	2
82263	1.06	0.02	2	0.15	0.04	7	0.15	0.03	3	0.45	0.09	3	0.568	0.103	2

PBMCs, peripheral blood mononuclear cells. ¹Normal fibroblasts. ²Leukemia cell line. ³Multiple myeloma cell line.