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. Author manuscript; available in PMC: 2014 May 15.
Published in final edited form as: J Am Chem Soc. 2013 May 3;135(19):7223–7234. doi: 10.1021/ja3125417

Figure 2.

Figure 2

Interconversion of 5a-5d in MeCN-H2O. Panels A to D show isomerization of compounds 5a-5d. The proportion of compounds is on the Y axis and reaction time is on the X axis. Conditions: Trifluoroacetate salts (0.1 mg) of the amine were placed in 0.25 mL of 50% aqueous MeCN. Purity was analyzed at the indicated time points by analytical reverse phase HPLC.