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. Author manuscript; available in PMC: 2014 May 15.
Published in final edited form as: J Am Chem Soc. 2013 May 3;135(19):7223–7234. doi: 10.1021/ja3125417

Figure 5.

Figure 5

Isomerization of 5a-5d in Binding Assay Medium. Panels A to D correspond to isomerization studies of isomers 5a-5d. The proportion of compounds is on the Y axis and reaction time is on the X axis. Conditions: the individual sample 5a, 5b, 5c or 5b (0.1 mg) was dissolved in binding medium (0.25 mL) and the samples were incubated at room temperature. The solution of corresponding isomer in binding medium was directly analyzed in analytical reverse phase HPLC at the indicated time points.