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. Author manuscript; available in PMC: 2014 Apr 11.
Published in final edited form as: J Med Chem. 2013 Mar 22;56(7):3048–3067. doi: 10.1021/jm4001105

Table 4.

Cell growth inhibitory activity of compounds 31, 32, 1 and 2 in three small-cell lung cancer cell lines

Cell Lines IC50 ± SD (nM)

1 2 31 32
H1963 54.0±28.2 26.6±7.9 8.2±4.9 1.0±0.5
H187 137.7±71.3 38.4±26.8 7.9±3.9 1.4±1.3
H1417 173.4±122.1 54.2±11.1 11.1±2.0 2.3±0.2