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. Author manuscript; available in PMC: 2014 Aug 1.
Published in final edited form as: Hypertension. 2013 May 28;62(2):367–374. doi: 10.1161/HYPERTENSIONAHA.113.01236

Figure 3. Effect of endothelium on NS309-induced relaxation.

Figure 3

Immunoreactivity of eNOS was present in endothelium-intact arteries (Panel A) but absent in endothelium-denuded arteries (Panel B), demonstrating the effectiveness of endothelium removal. C. NS309-induced relaxation of norepinephrine (NE, 3 μmol/L)-contracted pregnant uterine arteries with (EC intact) or without (EC removal) endothelium. Data are means ± SEM of tissues from 4–6 animals in each group. Immunoreactivity of SK2 (Panel D) and SK3 (Panel F) channels in endothelium (EC) and vascular smooth muscle (SM) of pregnant uterine arteries. Panels E and G show negative controls of SK2 and SK3 staining.