Table III.
Trends in cystic neoplasms during a 33-year time period
| Factor | 1978–1989 | 1990–1994 | 1995–1999 | 2000–2004 | 2005 to present |
|---|---|---|---|---|---|
| n | 67 | 58 | 120 | 230 | 376 |
| Incidental diagnosis, % | 22 | 6.8 | 28.3 | 45.7 | 49.7 |
| Abdominal pain, % | — | 35.6 | 50.8 | 37.4 | 36.5 |
| Jaundice, % | 10.4 | 11.9 | 10.8 | 6.5 | 5.3 |
| Weight loss, % | — | 8.5 | 25.8 | 12.6 | 10.4 |
| Pancreatitis, % | — | 16.9 | 20 | 7.8 | 14.9 |
| Diagnostic tests, % | |||||
| MR | 0 | 1.7 | 4.2 | 18.3 | 30.6 |
| ERCP | 59 | 25.4 | 35.8 | 17.4 | 12 |
| EUS | 0 | 6.8 | 28.3 | 47.4 | 55.3 |
| Cytology | 8.9 | 15.3 | 17.5 | 35.2 | 35.9 |
| Pathological diagnoses, n, % | |||||
| SPN | 0% | 0% | 4, 3.3% | 7, 3.0% | 18, 4.8% |
| PDAC | 0% | 0% | 0% | 3, 1.3% | 4, 1.1% |
| MD–IPMN | 2, 3.0% | 5, 8.6% | 30, 25.0% | 43, 18.7% | 100, 26.6% |
| BD–IPMN | 0% | 0% | 10, 8.3% | 52, 22.6% | 84, 22.3% |
| MCN | 42, 62.7% | 15, 25.9% | 34, 28.3% | 48, 20.9% | 60, 16.0% |
| SCA | 18, 26.9% | 17, 29.3% | 24, 20.0% | 34, 14.8% | 44, 11.7% |
| CNEN | 2, 3.0% | 1, 1.7% | 7, 5.8% | 20, 8.7% | 32, 8.5% |
| Other | 3, 4.4% | 20, 34.5% | 11, 9.2% | 23, 10% | 34, 9.0% |
| Malignant, % | 41 | 15.5 | 27.5 | 12.2 | 11.7 |
| Procedures performed, n, % | |||||
| Pancreatoduodenectomy | 29, 43.3% | 24, 41.4% | 54, 45.0% | 113, 49.1% | 148, 39.4% |
| Middle pancreatectomy | 0% | 3, 5.1% | 8, 6.7% | 18, 7.8% | 34, 9.0% |
| Distal pancreatectomy | 25, 37.3% | 26, 44.9% | 52, 43.3% | 86, 37.4% | 184, 48.9% |
| Other | 13, 19.4% | 5, 8.6% | 6, 5.0% | 13, 5.7% | 10, 2.7% |
BD–IPMN, Branch duct intraductal papillary mucinous neoplasm; CNEN, cystic neuroendocrine neoplasm; ERCP, endoscopic retrograde cholangiopan-creatography; EUS, endoscopic ultrasound; MCN, mucinous cystic neoplasm; MD–IPMN, main-duct intraductal papillary mucinous neoplasm; MR, magnetic resonance; PDAC, pancreatic ductal adenocarcinoma; SCA, serous cystadenoma; SPN, solid pseudopapillary neoplasm.