Table 1.
Summary of individual tumor data.
| Fibroid | Size (cm) | Collagenb (%) | Mitoses | PCNA (%) | Factor 8 (microvessel density) |
|---|---|---|---|---|---|
| Phasea 1 | |||||
| 1a | <2 | 1.14 | 1 | 24.3 | 92 |
| 2a | >2 | 0.17 | 0 | 54.7 | 79.2 |
| 3a | <2 | 1.86 | 1 | 69.9 | 113.0 |
| 4a | >2 | 0.61 | 0 | 35.2 | 56.6 |
| 5a | <2 | 0.37 | 0 | 59.1 | 119 |
| Average | 2 > 2 cm | 0.83% | 0.4 | 48.6 | 92 |
|
| |||||
| Phase 2 | |||||
| 1b | 1.5 × 1.0 × 1.0 | 5.11 | 0 | 18.1 | 45.0 |
| 2b | >2 | 6.04 | 0 | 13.4 | 99.6 |
| 3b | >2 | 11.89 | 0 | 56.9 | 40.2 |
| 4b | 4.0 × 3.0 × 2.5 | 3.33 | 1 | 25.3 | 25.4 |
| 5b | 1.8 × 1.9 × 1.0 | 14.64 | 1 | 48.8 | 73.6 |
| Average | 3 > 2 cm | 8.20% | 0.4 | 32.5 | 57 |
|
| |||||
| Phase 3 | |||||
| 1c | >2 | 30.81 | 0 | 3.1 | 27.0 |
| 2c | 4.0 × 5.0 × 3.0 | 36.55 | 0 | 8.2 | 8.8 |
| 3c | >2 | 33.36 | 0 | 19.1 | 27.6 |
| 4c | 7.3 × 6.5 | 29.99 | 2 | 50.2 | 66.8 |
| 5c | 3.5 × 3.0 × 2.0 | 38.41 | 0 | 47.6 | 56.4 |
| Average | 5 > 2 cm | 33.82% | 0.4 | 25.6 | 40 |
|
| |||||
| Phase 4 | |||||
| 1d | 3.0 × 3.0 | 50.02 | 0 | 13.8 | 29.0 |
| 2d | 6.0 × 5.0 × 4.0 | 72.65 | 0 | 19.1 | 43.6 |
| 3d | ≥2.0 | 51.76 | 0 | 20.3 | 18.8 |
| 4d | 14 × 7.5 | 67.42 | 0 | 6.3 | 40.8 |
| 5d | 5 × 4.5 | 58.11 | 0 | 15.5 | 31.6 |
| Average | 5 > 2 cm | 59.99% | 0.0 | 15.0 | 33 |
aPhase was based upon light microscopic estimation of the percentage of collagen in the tumor in H&E-stained slides.
bCollagen (%) was determined by image analysis of Masson's trichrome-stained slides.