A) Pro-survival factor expression in IL-6 stimulated T cells. Purified LN T cells
were incubated overnight in medium, IL-7 or IL-6. mRNA expression of the
indicated genes were assessed by qRT-PCR. Data show the mean +/−
SEM of three independent experiments.
(B) Immunoblot analysis of Mcl-1 expression in cytokine stimulated cells.
Purified LN T cells were incubated with IL-6, IL-7 or in medium alone for 24
hours, and total cell lysates were probed for Mcl-1 and then reprobed for
β-actin as loading control. Numbers in box indicate relative Mcl-1
expression as determined by densitometry of the bands. Blot is representative of
two independent experiments.