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. Author manuscript; available in PMC: 2014 Nov 1.
Published in final edited form as: Cytokine. 2013 Aug 26;64(2):10.1016/j.cyto.2013.08.001. doi: 10.1016/j.cyto.2013.08.001

Fig. 4. IL-6 promotes peripheral T cell homeostasis.

Fig. 4

(A) LN T cell numbers in IgHKO and IgHKOIL6Tg mice. Data show the mean +/− SEM of five independent experiments with a total of seven IgHKO and eight IgHKOIL6Tg mice.

(B) LN cell analysis of IgHKO and IgHKOIL6Tg mice. Histograms show TCRβ expression of total LN cells (top). Contour plots show CD4/CD8 profiles of TCRβ+ gated LN T cells. Results are representative of five independent experiments with seven IgHKO and eight IgHKOIL6Tg mice.

(C) CD4/CD8 ratio of LN T cells. Data show mean +/− SEM of four independent experiments with a total of seven IgHKO and six IgHKOIL6Tg mice.

(D) Cytokine receptor expression on IgHKO and IgHKOIL6Tg T cells. Surface IL-6Rα and IL-7Rα levels were quantified in MFI. Bar graphs show the mean +/− SEM of four independent experiments with seven IgHKO and six IgHKOIL6Tg mice.