(A) LN T cell numbers in IgHKO and IgHKOIL6Tg
mice. Data show the mean +/− SEM of five independent experiments
with a total of seven IgHKO and eight
IgHKOIL6Tg mice.
(B) LN cell analysis of IgHKO and IgHKOIL6Tg
mice. Histograms show TCRβ expression of total LN cells (top). Contour
plots show CD4/CD8 profiles of TCRβ+ gated LN T
cells. Results are representative of five independent experiments with seven
IgHKO and eight IgHKOIL6Tg mice.
(C) CD4/CD8 ratio of LN T cells. Data show mean +/− SEM of four
independent experiments with a total of seven IgHKO and six
IgHKOIL6Tg mice.
(D) Cytokine receptor expression on IgHKO and
IgHKOIL6Tg T cells. Surface IL-6Rα and
IL-7Rα levels were quantified in MFI. Bar graphs show the mean
+/− SEM of four independent experiments with seven
IgHKO and six IgHKOIL6Tg mice.