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Oncology biomarkers in one carbon metabolism
| Biomarker | Source | Use |
|---|---|---|
| Choline | C11 Pet Imaging | Detection of advanced malignancies |
| Sarcosine | Urine Metabolite | Possible predictor of metastatic prostate cancer |
| Thymidylate Synthase | Tumor mRNA expression | Expression Correlates with response to 5-Fluorouracil |
| Glutathione sulfer transferase | Tumor mRNA expression | FDA-approved as part of assay for decision to use chemotherapy in Estrogen Receptor Positive Breast Cancer |
