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. 2013 Oct 1;2013:813450. doi: 10.1155/2013/813450

Figure 5.

Figure 5

Pretreatment with α-ZAL reduced the expression and activity of caspase-9 in homocysteine-challenged HUVECs. The expression and activity of caspase-9 were significantly increased after treatment with 500 μmol/L homocysteine for 24 h. Pretreatment with α-ZAL could attenuate this effect. (a) Expression of caspase-9 (Western blot). (b) Activity of caspase-9 (chemiluminescence). Data were presented as mean ± SD. *P < 0.05 versus Vehicle, # P < 0.05 versus Hcy alone. α-ZAL: α-zearalanol; 17β-E2: 17β-estradiol; Hcy: homocysteine.