Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Pretreatment with α-ZAL reduced the expression of 3-nitrotyrosine in homocysteine-challenged HUVECs (Western blot). The expression of 3-nitrotyrosine was significantly increased after treatment with 500 μmol/L homocysteine for 24 h. Pretreatment with α-ZAL could attenuate this effect. Data were presented as mean ± SD. *P < 0.05 versus Vehicle, # P < 0.05 versus Hcy alone. α-ZAL: α-zearalanol; 17β-E2: 17β-estradiol; Hcy: homocysteine; 3-NT: 3-nitrotyrosine.
