Table 4.
Summary of the sensitivity and concordance of analysis of DNA isolated from urine by quantitative polymerase chain reaction and small-molecule FGFR3
qPCR tumor | qPCR urine | smFGFR3-urine | |
---|---|---|---|
Sensitivity | 58% (11/19) (95% CI 36%–77%) |
32% (6/19) (95% CI 15%–54%) |
79% (15/19) (95% CI 57%–92%) |
Concordance | – | 46% (5/11) (95% CI 21%–72%) |
91% (10/11) (95% CI 62%–98%) |
Abbreviations: CI, confidence interval; qPCR, quantitative polymerase chain reaction; smFGFR3, small-molecule FGFR3.