Table 5.
Changes in liver function in ConA-induced hepatitis after the Nec-1 intervention (means ± SD).
| Groups | Number of animals (n) | ALT (U/L) | AST (U/L) | ||||
|---|---|---|---|---|---|---|---|
| 8 h | 12 h | 20 h | 8 h | 12 h | 20 h | ||
| Vehicle | 30 | 803 ± 133 | 1972 ± 199 | 535 ± 68 | 502 ± 158 | 733 ± 110 | 528 ± 107 |
| ConA model | 30 | 857 ± 92 | 1996 ± 126 | 507 ± 72 | 506 ± 232 | 730 ± 117 | 507 ± 72 |
| Nec-1 intervention | 30 | 441 ± 68* | 616 ± 128* | 259 ± 47* | 219 ± 72# | 461 ± 90# | 212 ± 58# |
Notes. ALT compared with the Nec-1-, vehicle-, and ConA-treated groups, *P < 0.05; AST compared with the Nec-1-, vehicle-, and ConA-treated groups, # P < 0.05.