Fig. 1.
A) Timeline of study procedures. Day 1: screening for psychiatric and medical history and setting US. Level ranged from .5 to 5.0 mA and self-determined to be “highly annoying but not painful”. Day 2: fear conditioning task: habituation (10 colored circles alone) was followed by acquisition (10 colored circles that were paired (CS+) or unpaired (CS−)) with US (US duration: 500 ms shock; CS duration: 8 s, intertrial interval (ITI) = 20 − 5 s). (B) Diagram to represent timing and measurement within the conditioned stimuli (CS+ and CS−) trial types during Acquisition. The SC response score for each CS interval was obtained by subtracting the mean level for the 2 s immediately preceding CS onset from the highest value among those recorded during the 8 s CS interval. The SC response score for the interval containing the UCR was obtained by subtracting the average SC level within 6–8 s following CS onset, from the maximum increase in SC level during the .5–6.5 s interval following CS offset (corresponding to the onset of the .5 s US).