Table 6.

WGEE estimates of parameters, standard errors, and p-values from FRM-based ZIP model with treatment by time interaction based on Wald and score tests under MAR and MMDP for the CTN0018 Study.

Results of FRM-based ZIP model for CTN0018 study
			P-value for H0 : β = 0
Parameter	Estimate	Standard errors	Wald	Score
Log-linear part (μit)
β 0	2.69	0.196	< 0.001	< 0.001
β1 (intervention)	−0.08	0.028	< 0.001	< 0.001
β2 (baseline USO)	0.012	0.001	< 0.001	< 0.001
β3 (time)	−0.017	0.118	0.885	0.883
β4(intervention*time)	−0.062	0.187	0.742	0.741
Logistic part (ρit)
βu 0	−0.52	0.354	0.142	0.140
βu1 (intervention)	0.301	0.499	0.564	0.562
βu2 (baseline USO)	−0.017	0.004	< 0.001	< 0.001
βu3(time)	0.126	0.221	0.568	0.566
βu4(intervention*time)	−0.121	0.314	0.701	0.700