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. 2013 Oct 18;62(11):3766–3774. doi: 10.2337/db13-0345

FIG. 4.

FIG. 4.

Identification of clinical responders to teplizumab. A: The cumulative frequency of subjects and distribution of percentage decrease from baseline C-peptide AUC at month 24. The arrow shows the smallest percentage loss of C-peptide AUC in the control group. B: The C-peptide AUC at each time point (means ± 25th and 75th percentiles) is shown for the responders (red line) and nonresponders (green line) in the drug-treated group and for the control subjects (blue line). ***P < 0.001 between responders and nonresponders at each time point based on ANCOVAs.