FIG. 1.
Intestinal growth and glucose absorption are increased in adult db/db mice and can be reversed by CR. A: Food intake in db/db and db/+ mice. B: Body weight in db/db, db/+, and db/CR mice. C: Whole length of small intestine in db/db, db/+, and db/CR mice. D: Small intestine weight per cm length in db/db, db/+, and db/CR mice. E: Glucose uptake in jejunal rings of 8-week-old db/db, db/+, and db/CR mice. Counts are expressed as μmol/L per cm. F and G: Intestinal GLUT2 protein expression in 8-week-old db/db, db/+, and db/CR mice. Western blot data from at least three independent experiments and are expressed as mean ± SEM; mice n = 5–8 per group. *P < 0.05, **P < 0.01.