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Compound 7f was not toxic to normal human mammary epithelial cells (HMEC). HMEC cells were treated with different concentrations of Dox or 7f for either 24 h or 72 h. For those cells treated with drugs for 24 h, the cells were further incubated in drug-free media for 48 h. At the end of the 72 h incubation period, the number of viable cells was quantified by an MTT assay. The data are presented as mean ± SD of a representative experiment performed in triplicates.
